Khapre® S: Skin Formula Range

Khapre® S: Skin          Formula Range

Khapre® – S

Practitioners: please page down to view scientific comparison studies and page source references

Our skin suffers inflammation and bacterial attack for a multitude of reasons. Often environmental and dietary factors can be a major cause of skin irregularities resulting in premature skin aging and acne.

The anti-aging products market is traditionally resilient to economic cycles and reported to reach $291.9 Billion globally by 2015(1). Some single anti-acne brands have global sales in excess of $1.5 Billion annually(1b).

Scientific studies(1a) show that the Khapre® – S  prime ingredient possesses significant anti-inflammatory activity on acute and chronic inflammation via oral & topical application. In addition, the antinociceptive pain relief properties provide a measure of soothing relief for sensitive skin(2).

 

Skin Formula 1 – Anti Aging

Khapre® – S anti-aging  is an anti-aging skin formula designed as a key ingredient for skin creams with high potency natural anti-oxidant(3) and anti-inflammatory(4) properties.

Scientific studies reveal: ease of emulsification, good spreadability, consistency, emollient property and ability to be easily washed off the skin. These properties confirm the rejuvenation & skin softening characteristics(6)(7).

The oral formulation(8) is Khapre® – S anti-aging

The topical formulation is Khapre® – S anti-aging cream

 

Skin Formula 2 – Acne Management

Khapre® – S acne-assist  is an anti-acne skin formula with a combination of anti-microbial(5) and anti-inflammatory(4) action with other phyto-nutrients(5) makes it an ideal key ingredient in anti-acne formulations.

A unique part of an acne management program, the pain relieving properties(2) are quietly at work, helping you to concentrate on the daily tasks ahead.

Scientific studies reveal: ease of emulsification, good spreadability, consistency, emollient property and ability to be easily washed off the skin. These properties confirm the rejuvenation & skin softening characteristics(6)(7).

The oral formulation(8) is Khapre® – S acne-assist

The topical formulation is Khapre® – S acne-assist gel


Disclaimer: Please note that any statements aligned to product descriptions on this website and the products themselves are in varying stages of evaluation by the Therapeutic Goods Administration in Australia (TGA) & the Food and Drug Administration in the United States of America (FDA). These products are not intended to diagnose, treat, cure or prevent any disease. 

Bioactive recommend the three pillars of health, a balanced diet with plenty of fresh filtered water, regular daily exercise and a good night’s sleep.


(1a) Contact Us to find out more

 


Scientific studies: To view scientific studies comparing Bioactive extracts to other pharmaceutical substances click on Bioactive Research

Page references:

(1) http://www.worldhealth.net/news/global_anti-aging_products_market_to_rea/

  • “Global Anti-Aging Products Market to Reach $291.9 Billion by 2015, According to New Report by Global Industry Analysts”
  • “Anti-aging products market is traditionally resilient to economic cycles, given consumers’ unchanging desire to look young and healthy, and the importance accorded to health, and well-being.”

(1b) http://www.guthy-renker.com.au/Company-Profile.aspx

  • “Today, the Guthy-Renker Corporation is one of the world’s most successful privately owned direct response companies, with annual sales of more than US$1.5 billion dollars.”  (Primarily from anti-acne product sales of Proactiv brand which is a registered trademark of Guthy-Renker Corporation)

(2) Source: “Conclusion: In all experimental models used in this study, AKS – Aqueous stem bark extract of Khaya Senegalensis exhibited significant anti-inflammatory and antinociceptive (pain relief) properties which compare favourably well with the effects produced by the standard drugs used. These findings provide scientific basis to justify the traditional use of the plant in inflammatory diseases. The study showed that Khaya senegalensis is a medicinal plant with good potential for the development of new anti-inflammatory drugs. “; Kolawole OT, Akiibinu MO, Ayankunle AA and Awe EO., 2013. Evaluation of Anti-inflammatory and Antinociceptive Potentials of Khaya senegalensis A. Juss (Meliaceae) Stem Bark Aqueous Extract. British Journal of Medicine & Medical Research, 3(2): 216-229, 2013

(3) Source: Bioactive Solutions blind studies conducted in an independent laboratory concluded an anti-oxidant profile in excess of 95%.

(4) Source: Bioactive Solutions blind studies conducted in an independent laboratory concluded an anti-inflammatory COX2 & Caspase 3 marker profile averaging in excess of 95% effective; (Bioactive Solutions Pty Ltd Australian Innovation Patent Application No. 2013100366).

(5) Source: Other phyto-nutrients are sourced from Khaya Senegalensis seed oil. Bioactive Solutions Laboratory tests conclude the fatty acid profile of Khaya Senegalensis seed oil averages the following:

  • Omega-9 (Oleic Acid): 60.60%;
  • Omega-6 (Linoleic Acid): 5.90%;
  • Omega-3 (Linolenic Acid): 0.43%;
  • Palmic Acid: 9.20%;
  • Stearic Acid: 12.20%;
  • The total oil content averages 38.40%;
  • The moisture content averages 5.27%.

The fatty acid profile is similar to that found in the profile ranges of Olive oil, Sunflower oil and Canola oil varieties.

(6) J D Audu-Peter, P O Olorunfemi, N Njoku; ‘Antimicrobial and pharmaceutical properties of Khaya senegalensis seed oil’, Journal of Pharmacy and Bioresources Vol. 3 (1) 2006: pp. 19-24

(7) Safe to use: Traditional medicine applications over centuries classify the Khapre®  ingredients as GRAS (Generally Regarded As Safe). In addition, Bioactive has undertaken stringent safety profiling on their own organic & 3rd party supply of plant material to confirm the traditional safety claims. Reference source:

  • Bioactive Solutions conducted Cytotoxicity, Mediator release, TNFalpha induced PGE2 expression Assays on their own organic supply of plant material which registered negative for cell death (cytotoxicity).
  • Reference is also sited to the following papers:
    • R. G. Ayo, O. T. Audu and J. O. Amupitan, 2007; Physico-chemical characterization and cytotoxicity studies of seed extracts of Khaya senegalensis (Desr.) A. Juss. African Journal of Biotechnology Vol. 6 (7), pp. 894-896, 2 April 2007;
    • OJO, O. O.1, NADRO, M. S.2 and TELLA, I. O., 2006; Protection of rats by extracts of some common Nigerian trees against acetaminophen-induced Hepatotoxicity; African Journal of Biotechnology Vol. 5 (9), pp. 755-760, 2 May 2006
    • J D Audu-Peter, P O Olorunfemi, N Njoku; 2006; Antimicrobial and pharmaceutical properties of Khaya senegalensis seed oil; Journal of Pharmacy and Bioresources Vol. 3 (1) 2006: pp. 19-24

(8) Taken as an oral formulation, traditional medicine side effects may include diarrhoea, polyuria and general weakness . These side effects are thought to be indicative of the general de-tox properties of the Khapre®-S  ingredients.  As in any de-tox preparation, additional fresh water should always be consumed. If they persist see your doctor. Reference source: Side effects from traditional medicine: Tchacondo T. Et al, pub 2010. Herbal Remedies and Their Adverse Effects in Tem Tribe Traditional Medicine in Togo. African Journal of Traditional, Complementary and Alternative Medicines, 2011;8(1):45-60.