Khapre® O: Oral Formula

Khapre® O: Oral Formula

Khapre® O

Practitioners: please page down to view scientific comparison studies and page source references

Khapre® O is an oral formula used to reduce inflammation of the mouth & gums including mouth ulcer pain relief & repair(1a).

A proprietary solution inclusive of the patented Khapre® formula(1) creates a gentle and soothing oral environment, high in natural anti-microbial, anti-inflammatory, & anti-oxidant compounds.

Scientific studies show that it’s prime ingredient possesses significant anti-inflammatory & pain relieving activity on acute and chronic inflammation via oral application(3).

Three products are under development:

  1. An gel concentrate for direct mouth ulcer application to help with rapid pain relief & repair;
  2. A handy spray application to be applied frequently through out the day, often a necessity before & after food to assist with pain relief & repair;
  3. A ‘sore throat’ gargle providing rapid pain relief and reduced swelling often associated with ‘silent’ reflux of stomach acids causing ulceration towards the back of the throat.

Disclaimer: Please note that any statements aligned to product descriptions on this website and the products themselves are in varying stages of evaluation by the Therapeutic Goods Administration in Australia (TGA) & the Food and Drug Administration in the United States of America (FDA). These products are not intended to diagnose, treat, cure or prevent any disease.

Bioactive recommend the three pillars of health, a balanced diet with plenty of fresh filtered water, regular daily exercise and a good night’s sleep.


(1a) Contact Us to find out more


Scientific studies: To view scientific studies comparing Bioactive extracts to other pharmaceutical substances click on Bioactive Research

Page references:

(1)      Source: Bioactive blind studies conducted in an independent laboratory concluded an anti-inflammatory COX2 & Caspase 3 marker profile averaging in excess of 95% effective as an inflammatory inhibitor; (Bioactive Solutions Pty Ltd Australian Innovation Patent Application No. 2013100366).

(2)      Source:

  • Low potency Khapre-DS + KS seed oil;
  • Other phyto-nutrients are sourced from KS seed oil. Bioactive Solutions independent laboratory tests conclude the fatty acid profile of KS seed oil averages the following:
    • Omega-9 (Oleic Acid): 60.60%;
    • Omega-6 (Linoleic Acid): 5.90%;
    • Omega-3 (Linolenic Acid): 0.43%;
    • Palmic Acid: 9.20%;
    • Stearic Acid: 12.20%;
    • The total oil content averages 38.40%;
    • The moisture content averages 5.27%.
  • The fatty acid profile is similar to that found in the profile ranges of Olive oil, Sunflower oil and Canola oil varieties.

(3) Source: “Conclusion: In all experimental models used in this study, AKS – Aqueous stem bark extract of Khaya Senegalensis exhibited significant anti-inflammatory and antinociceptive (pain relief) properties which compare favourably well with the effects produced by the standard drugs used. These findings provide scientific basis to justify the traditional use of the plant in inflammatory diseases. The study showed that Khaya senegalensis is a medicinal plant with good potential for the development of new anti-inflammatory drugs. “; Kolawole OT, Akiibinu MO, Ayankunle AA and Awe EO., 2013. Evaluation of Anti-inflammatory and Antinociceptive Potentials of Khaya senegalensis A. Juss (Meliaceae) Stem Bark Aqueous Extract. British Journal of Medicine & Medical Research, 3(2): 216-229, 2013

(4) Source:

  • Bioactive blind studies conducted in an independent laboratory concluded an anti-oxidant marker profile in excess of 95% effective.
  • “This strong antioxidant activity is comparable to that of BHT: antioxidant food additive E321, regarding the DPPH free scavenging activity”, (E321 is approved by the European Union and the FDA) Quote from paper: Zhang H. December 2008; CHARACTERIZATION OF BIOACTIVE PHYTOCHEMICALS FROM THE STEM BARK OF AFRICAN MAHOGANY Khaya senegalensis (MELIACEAE); A PhD Food Technology Dissertation Presented to the Graduate School of Clemson University, Clemson, South Carolina USA.

(5) Taken as an oral formulation, traditional medicine side effects may include diarrhoea, polyuria and general weakness . These side effects are thought to be rare but indicative of the general de-tox properties of the Khapre-O™  ingredients.  As in any de-tox preparation, additional fresh water should always be consumed. If they persist see your doctor. Reference source: Side effects from traditional medicine: Tchacondo T. Et al, pub 2010. Herbal Remedies and Their Adverse Effects in Tem Tribe Traditional Medicine in Togo. African Journal of Traditional, Complementary and Alternative Medicines, 2011;8(1):45-60.

(6) Source: Ojo OO, Nadro MS, Tella IO, 2006. Protection of rats by extracts of some common Nigerian trees against acetaminophen-induced hepatotoxicity. African Journal of Biotechnology Vol 5 (9), pp 755-760, 2 May 2006